Бактерии, ассоциированные с морскими губками — продуценты биологически активных веществ
Диссертация
Симбиоз микроорганизмов с морскими губками, возникший в поздний докембрийский период, является одним из древнейших на Земле (Finks, 1970; Ziegler, Rietschel, 1970; Wilkinson, 1984). Эволюция этого сообщества проходила на фоне увеличения содержания кислорода в атмосфере с 0,2% до 20% (Hadzi, 1963; Olson, 1981). Совместное существование губок и населяющих их микроорганизмов в течение длительного… Читать ещё >
Содержание
- Глава 1. Обзор литературы
- 1. 1. Особенности океанических экосистем как среды обитания микроорганизмов
- 1. 1. 1. Физико — химическая характеристика морской среды
- 1. 1. 2. Экологические особенности морских микроорганизмов
- 1. 2. Основные таксономические группы морских гетеротрофных бактерий
- 1. 3. Особенности микробных популяций, ассоциированных с гидробионтами
- 1. 3. 1. Особенности взаимоотношений микроорганизмов с губками
- 1. 4. Биологически активные вещества, синтезируемые морскими бактериями
- 1. 4. 1. Гидролитические ферменты
- 1. 4. 1. 1. Протеолитические ферменты
- 1. 4. 1. 2. Ферменты, гидролизующие сложные полисахариды морской среды
- 1. 4. 1. 3. Липолитические ферменты
- 1. 4. 1. 4. Ферменты нуклеинового обмена
- 1. 4. 2. Синтез биоактивных вторичных метаболитов
- 1. 4. 2. 1. Антибиотики и близкие к ним вещества
- 1. 4. 2. 2. Соединения токсического действия
- 1. 4. 2. 3. Антиопухолевые вещества
- 1. 4. 1. Гидролитические ферменты
- 1. 1. Особенности океанических экосистем как среды обитания микроорганизмов
- 2. 1. Объекты исследования
- 2. 2. Условия выделения и культивирования бактерий
- 2. 3. Методы изучения биологических свойств
- 2. 3. 1. Физиолого-биохимические признаки
- 2. 3. 2. Изучение ферментативной активности
- 2. 4. Методы исследования соединений антагонистического действия
- 2. 5. Методы геносистематики
- 3. 1. Таксономическая характеристика бактерий — ассоциантов
- 3. 1. 1. Таксономическое распределение биоактивных штаммов
- 3. 2. Сравнительные исследования продуцентов из различных районов Океана
- 4. 1. Распределение бактерий, синтезирующих гидролитические ферменты
- 4. 1. 1. Бактериальные продуцены щелочной фосфатазы
- 4. 1. 2. Бактериальные продуценты эластазы
- 4. 2. Бактериальные продуценты соединений антагонистического действия
- 4. 2. 1. Продуценты токсических и цитотоксических соединений
- 4. 2. 2. Продуценты соединений антимикробного действия
- 4. 2. 2. 1. Характеристика штаммов — продуцентов антифунгальных соединений
- 5. 1. Оптимизация состава среды культивирования
- 5. 2. Ускоренный метод поиска бактериальных продуцентов
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